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anticoagulation

Clinical teaching and practical ideas for your next study session.

Case Discussion

Acute Cholangitis on Warfarin: Separate Drainage From Sphincterotomy

With obstructed cholangitis and an INR of 3.2, the key procedural question is whether urgent duct decompression can be separated from sphincterotomy and stone extraction. Stent-only ERCP may be appropriate when the patient’s condition, anticoagulation, and technical feasibility favor staging—but the INR and procedure plan both need context.

Case Discussion

Apixaban Before Type A Aortic Dissection Repair: Protect the Bypass Plan

A recent apixaban dose complicates emergency Type A dissection repair. Learn how to assess residual drug, weigh reversal, and avoid compromising heparinization for cardiopulmonary bypass.

Medical Education

INR 11.2 Without Bleeding: Safe Warfarin Reversal Without Overcorrection

An INR above 10 is a management threshold, not a cue for indiscriminate reversal. Learn how to confirm truly absent bleeding, consider low-dose oral vitamin K, monitor the response, and restart anticoagulation safely.

Case Discussion

Sepsis-Associated Atrial Fibrillation: Is the Rhythm Causing Shock?

A fast irregular rhythm in sepsis may be the culprit, a consequence, or both. This case-based discussion teaches how to determine whether AF is driving instability, choose rate control versus synchronized cardioversion, and plan follow-up after recovery.

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