Explore the question bank
Internal Medicine curriculum
Browse the full curriculum by category, domain, topic, and subtopic, with question counts at every level.
Counts include individual SOE sub-questions. Questions may appear in more than one category; each is counted once in its pathway total.
Core
Core Internal Medicine
Basic Sciences
277 questions
Biochemistry, Metabolism & Nutrition
37 questions
Carbohydrate and lipid metabolism (clinically applied)
12 questions
Glycolysis/gluconeogenesis concepts
3 questions
Inborn errors (overview)
4 questions
Lipid metabolism
3 questions
Obesity and insulin resistance
2 questions
Micronutrients and deficiency syndromes
12 questions
Fat-soluble vitamins
3 questions
Refeeding syndrome
3 questions
Trace elements
3 questions
Water-soluble vitamins
3 questions
Protein metabolism and liver synthetic function
13 questions
Albumin and oncotic pressure
4 questions
Amino acid metabolism
4 questions
Bilirubin metabolism
3 questions
Coagulation factors synthesis
2 questions
Cellular & Molecular Biology
43 questions
Cell structure, organelles, and trafficking
15 questions
Cell cycle, apoptosis, necrosis
3 questions
Cell–cell junctions and extracellular matrix
4 questions
Membrane structure & transport
4 questions
Organelles and key functions
4 questions
Oncogenesis fundamentals
13 questions
Cancer immunology (intro)
3 questions
Carcinogenesis & exposures
3 questions
Hallmarks of cancer (board-level)
3 questions
Tumor suppressors and oncogenes
4 questions
Signal transduction & second messengers
15 questions
Inflammation signaling
4 questions
Pharmacologic implications
3 questions
Receptor classes
4 questions
Second messengers
4 questions
Epidemiology, Biostatistics & Evidence-Based Medicine
45 questions
Clinical guidelines and evidence synthesis
12 questions
Ethics in research
3 questions
GRADE and strength of recommendation
3 questions
Implementation and de-implementation
3 questions
Systematic reviews/meta-analyses
3 questions
Diagnostic test interpretation
10 questions
Bayesian reasoning
2 questions
Core measures
3 questions
ROC curves and thresholds
2 questions
Screening principles
3 questions
Study design and validity
13 questions
Bias and confounding
3 questions
Causality and inference
3 questions
Interventional trials
3 questions
Observational designs
4 questions
Treatment effects and risk
10 questions
Decision analysis basics
3 questions
Effect size measures
2 questions
Heterogeneity and subgroup analyses
3 questions
Time-to-event analysis
2 questions
Genetics & Genomics
31 questions
Complex traits and gene–environment interaction
10 questions
Epigenetics
3 questions
Microbiome (board-level concepts)
2 questions
Polygenic risk concepts
3 questions
Somatic mosaicism & clonal hematopoiesis
2 questions
Genomic testing in clinical practice
10 questions
Ethical issues
2 questions
Pharmacogenomics
3 questions
Testing modalities
2 questions
Variant interpretation
3 questions
Mendelian inheritance and risk
11 questions
Autosomal dominant patterns
3 questions
Autosomal recessive patterns
3 questions
Mitochondrial inheritance
2 questions
X-linked inheritance
3 questions
Immunology & Inflammation
36 questions
Adaptive immunity
12 questions
B cell biology and antibodies
4 questions
Hypersensitivity reactions
3 questions
T cell biology
3 questions
Vaccinology principles
2 questions
Autoimmunity and tolerance
12 questions
Central and peripheral tolerance
3 questions
Immunodeficiency overview
3 questions
Systemic autoimmune disease mechanisms
3 questions
Transplant immunology (intro)
3 questions
Innate immunity and inflammation
12 questions
Complement system
3 questions
Inflammation resolution
3 questions
Pattern recognition and cytokines
3 questions
Phagocytes and granulomatous inflammation
3 questions
Pathology & General Pathophysiology
35 questions
Cell injury and adaptation
12 questions
Amyloidosis (overview)
3 questions
Edema and effusions pathophysiology
3 questions
Inflammation and repair
3 questions
Reversible vs irreversible injury
3 questions
Fever, SIRS, and sepsis biology
12 questions
Biomarkers (concepts)
3 questions
Cytokine-mediated shock
3 questions
Organ dysfunction mechanisms
3 questions
Stress response and endocrine changes
3 questions
Hemostasis and thrombosis (mechanisms)
11 questions
Atherosclerosis & aneurysm pathophysiology
3 questions
Coagulation cascade (clinical interpretation)
3 questions
Platelet biology
2 questions
Thrombosis and embolism
3 questions
Physiology & Homeostasis
50 questions
Cardiovascular physiology
13 questions
ECG electrophysiology basics
4 questions
Exercise physiology
3 questions
Hemodynamics and cardiac output
3 questions
Vascular biology
3 questions
Endocrine physiology
14 questions
Calcium and bone metabolism
4 questions
Glucose homeostasis
4 questions
Hypothalamic–pituitary axes
3 questions
Thyroid hormone action
3 questions
Renal physiology & volume regulation
12 questions
Acid–base renal handling
3 questions
Glomerular filtration and hemodynamics
3 questions
Tubular handling of electrolytes
3 questions
Water balance
3 questions
Respiratory physiology
11 questions
Acid–base and respiratory compensation
3 questions
Hypoxic pulmonary vasoconstriction
2 questions
Lung mechanics
3 questions
Ventilation/perfusion and gas exchange
3 questions
Cardiopulmonary Medicine
191 questions
Cardiology: Ischemia, Heart Failure, Valves, Rhythm
68 questions
Acute coronary syndromes
9 questions
ACS complications
3 questions
Diagnosis and initial management
2 questions
Reperfusion strategies
2 questions
Secondary prevention
2 questions
Arrhythmias and conduction disorders
12 questions
Atrial fibrillation/flutter
3 questions
Bradyarrhythmias and blocks
3 questions
Supraventricular tachycardias
3 questions
Ventricular arrhythmias
3 questions
Heart failure (acute and chronic)
13 questions
Acute decompensated HF management
3 questions
Advanced therapies and devices (overview)
3 questions
Classification and etiologies
3 questions
Guideline-directed medical therapy (GDMT) concepts
4 questions
Pericardial and myocardial disease
12 questions
Cardiomyopathies (overview)
3 questions
Myocarditis
3 questions
Pericarditis and effusion
3 questions
Pulmonary embolism strain vs MI differentiation
3 questions
Stable ischemic heart disease and angina
10 questions
Diagnostic evaluation
2 questions
Medical therapy
3 questions
Pathophysiology and symptom patterns
2 questions
Revascularization concepts
3 questions
Valvular heart disease
12 questions
Aortic regurgitation and mitral stenosis
3 questions
Aortic stenosis
3 questions
Endocarditis-related valvular issues (interface)
3 questions
Mitral regurgitation
3 questions
Pulmonology: Airways, Parenchyma, Pleura, Critical Respiratory
74 questions
Asthma
12 questions
Acute exacerbation management
3 questions
Chronic management
3 questions
Complications and mimics
3 questions
Diagnosis and phenotypes
3 questions
COPD
12 questions
Acute exacerbations
3 questions
Complications
3 questions
Diagnosis and staging
3 questions
Stable management
3 questions
Interstitial lung disease (ILD) and pulmonary fibrosis
13 questions
Acute exacerbation of ILD
3 questions
Diagnostic workup
3 questions
ILD pattern approach
4 questions
Management concepts
3 questions
Pleural disease
12 questions
Empyema and complicated parapneumonic effusion
3 questions
Malignant pleural effusion
3 questions
Pleural effusion evaluation
3 questions
Pneumothorax
3 questions
Pneumonia and lower respiratory infections
14 questions
Aspiration syndromes
3 questions
Community-acquired pneumonia
4 questions
Hospital-acquired and ventilator-associated pneumonia
4 questions
Opportunistic pneumonias (overview)
3 questions
Respiratory failure and ventilatory support (intro)
11 questions
Hypercapnic respiratory failure
3 questions
Hypoxemic respiratory failure
3 questions
Noninvasive ventilation basics
2 questions
Sleep-disordered breathing (overview)
3 questions
Vascular Medicine & Hypertension
49 questions
Aortic disease
13 questions
Acute aortic syndromes overview
4 questions
Aneurysms
3 questions
Aortic dissection
3 questions
Peripheral arterial disease
3 questions
Hypertension (diagnosis and management)
14 questions
Accurate measurement and diagnosis
4 questions
First-line therapies and combinations
3 questions
Hypertensive emergencies/urgencies
4 questions
Secondary hypertension causes
3 questions
Pulmonary hypertension and RV failure (interface)
10 questions
PH classification overview
3 questions
PH diagnostic tests (overview)
2 questions
RV failure physiology and treatment principles
3 questions
Targeted therapies (overview)
2 questions
Venous thromboembolism
12 questions
Complications and recurrence prevention
3 questions
DVT diagnosis and treatment
3 questions
Pulmonary embolism
3 questions
Thrombophilia and special situations
3 questions
Clinical Pharmacology
166 questions
Core Principles of Clinical Pharmacology
88 questions
Adverse drug reactions (ADRs) and safety
12 questions
ADR classification and recognition
3 questions
Medication errors and reconciliation
3 questions
Organ-specific toxicities
3 questions
Pregnancy/lactation and teratogenicity
3 questions
Clinical toxicology and overdose
13 questions
Alcohols and gases
3 questions
Cardiotoxic ingestions
4 questions
Common high-yield overdoses
3 questions
Initial approach to poisoning
3 questions
Dosing in renal/hepatic impairment
11 questions
Assessing kidney function for dosing
2 questions
Hepatic impairment dosing
3 questions
Obesity and underweight dosing
4 questions
Renal dose adjustments (principles)
2 questions
Drug–drug and drug–food interactions
13 questions
CYP-mediated interactions
4 questions
Herbals and supplements
3 questions
Pharmacodynamic interactions
3 questions
Transporters and chelation
3 questions
Pharmacodynamics (PD)
14 questions
Dose–response relationships
4 questions
Population variability
4 questions
Receptor pharmacology
3 questions
Time-dependent effects
3 questions
Pharmacokinetics (PK)
13 questions
Absorption and bioavailability
3 questions
Distribution
3 questions
Elimination
3 questions
Metabolism
4 questions
Therapeutic drug monitoring (TDM)
12 questions
Indications for TDM
2 questions
Key monitored drugs
4 questions
Sampling and interpretation
3 questions
TDM in special populations
3 questions
Major Therapeutic Classes in Internal Medicine
78 questions
Anticoagulants and antiplatelets
14 questions
Antiplatelet therapy
4 questions
DOACs
3 questions
Heparins and fondaparinux
5 questions
Warfarin
2 questions
Antimicrobials (overview for safe prescribing)
13 questions
Antifungals/antivirals
3 questions
Glycopeptides and lipopeptides
4 questions
Macrolides/fluoroquinolones/tetracyclines
3 questions
β-lactams
3 questions
Cardiovascular drugs
12 questions
Antianginal agents
4 questions
Antiarrhythmics
3 questions
Antihypertensives
2 questions
Heart failure therapies (foundational)
3 questions
CNS and pain medications
12 questions
Antidepressants/antipsychotics
3 questions
Antiepileptics
3 questions
Opioids and analgesic ladder
3 questions
Sedatives and hypnotics
3 questions
Endocrine and metabolic drugs
15 questions
Diabetes therapies
3 questions
Lipid-lowering therapies
3 questions
Steroids and adrenal drugs
5 questions
Thyroid therapies
4 questions
Immunomodulators and rheumatologic drugs
12 questions
Biologics and targeted therapies (overview)
3 questions
DMARDs (conventional)
3 questions
Transplant immunosuppression (overview)
3 questions
Vaccination and prophylaxis on immunosuppression
3 questions
Diagnostic Reasoning
133 questions
Clinical Reasoning Foundations
61 questions
Diagnostic error and safety
11 questions
Cognitive biases
2 questions
Safety nets
3 questions
Second opinions and escalation
3 questions
System factors
3 questions
Differential diagnosis building
12 questions
Illness scripts and pattern recognition
3 questions
Problem representation
2 questions
Red flags and must-not-miss diagnoses
4 questions
Systematic differentials
3 questions
History-taking for diagnosis
12 questions
Bias awareness in history
3 questions
Contextual history
3 questions
Functional and psychosocial assessment
2 questions
Symptom analysis frameworks
4 questions
Physical examination for decision-making
12 questions
Abdominal exam and acute abdomen screening
3 questions
Cardiopulmonary exam high-yield findings
3 questions
Neurologic screening and localization
3 questions
Vital signs and physiologic interpretation
3 questions
Probability and Bayesian reasoning at bedside
14 questions
Clinical prediction rules
5 questions
Decision thresholds
3 questions
Estimating pretest probability
3 questions
Using likelihood ratios
3 questions
Test Selection, Interpretation & Diagnostic Stewardship
72 questions
Chest imaging (CXR/CT basics)
12 questions
Common CT patterns
3 questions
CT indications and contrast considerations
2 questions
Diagnostic stewardship in imaging
3 questions
Systematic CXR approach
4 questions
ECG interpretation (core board patterns)
12 questions
Arrhythmia recognition
3 questions
Conduction and structural clues
3 questions
Electrolyte/drug effects
3 questions
Ischemia and infarction patterns
3 questions
Laboratory medicine fundamentals
12 questions
CBC interpretation
3 questions
Chemistry panels and liver tests
3 questions
Inflammatory and cardiac biomarkers
3 questions
Pre-analytical and analytical errors
3 questions
Microbiology diagnostics
12 questions
Blood cultures and contamination
3 questions
CSF interpretation
3 questions
Respiratory diagnostics
3 questions
Serology and immunologic tests pitfalls
3 questions
Pulmonary function tests and oxygenation
12 questions
ABG interpretation
3 questions
DLCO interpretation
3 questions
Pulse oximetry limitations
3 questions
Spirometry patterns
3 questions
Urinalysis and kidney diagnostics
12 questions
Dipstick and microscopy
4 questions
Imaging and biopsy indications (overview)
3 questions
Protein quantification
2 questions
Urine electrolytes
3 questions
Gastrointestinal Medicine
191 questions
Esophagus, Stomach, and Upper GI Bleeding
39 questions
Dysphagia and odynophagia
15 questions
Alarm features and cancer risk
3 questions
Initial diagnostic approach
3 questions
Mechanical obstruction vs motility disorder
4 questions
Oropharyngeal vs esophageal dysphagia
5 questions
GERD and peptic disorders
11 questions
Barrett esophagus
2 questions
Functional dyspepsia
3 questions
GERD diagnosis and management
3 questions
Peptic ulcer disease and H. pylori
3 questions
Upper GI bleeding
13 questions
Initial stabilization and risk stratification
3 questions
Non-variceal bleeding causes and management
4 questions
Special scenarios
3 questions
Variceal bleeding
3 questions
GI Oncology & Miscellaneous High-Yield Disorders
47 questions
Acute abdominal pain and surgical GI emergencies (overview)
10 questions
Appendicitis and diverticulitis
3 questions
Bowel obstruction
3 questions
GI perforation and peritonitis
2 questions
Mesenteric ischemia
2 questions
Colorectal cancer and polyposis syndromes (overview)
13 questions
Cancer prevention links
3 questions
Hereditary syndromes
3 questions
Presentation and workup
3 questions
Treatment concepts
4 questions
Motility and functional disorders (select)
12 questions
Acute intermittent porphyria (overview)
3 questions
Carcinoid syndrome (overview)
3 questions
Chronic nausea/vomiting differential
3 questions
Gastroparesis
3 questions
Pancreatic and hepatobiliary cancers (overview)
12 questions
Cancer-associated symptoms
3 questions
Cholangiocarcinoma and gallbladder cancer
3 questions
Hepatocellular carcinoma (HCC)
3 questions
Pancreatic adenocarcinoma
3 questions
Hepatobiliary, Pancreas, and Liver Failure
61 questions
Acute hepatitis and acute liver failure
12 questions
Acute liver failure management principles
2 questions
Fulminant infections in liver disease
3 questions
Toxic and ischemic hepatitis
4 questions
Viral hepatitis (A, B, C, E) overview
3 questions
Approach to abnormal liver chemistries
13 questions
Autoimmune and metabolic liver disease workup
3 questions
Drug-induced liver injury (DILI)
3 questions
Initial evaluation
3 questions
Pattern recognition
4 questions
Biliary disease
11 questions
Cholangitis
3 questions
Cholelithiasis and cholecystitis
3 questions
Cholestatic chronic diseases
3 questions
Gallstone pancreatitis interface
2 questions
Cirrhosis and portal hypertension
13 questions
Ascites and SBP
3 questions
Hepatic encephalopathy
3 questions
Hepatorenal syndrome (HRS)
3 questions
Varices and portal hypertensive bleeding prevention
4 questions
Pancreatitis and pancreatic disorders
12 questions
Acute pancreatitis diagnosis and severity
3 questions
Chronic pancreatitis
3 questions
Complications
3 questions
Initial management
3 questions
Small and Large Intestine: Diarrhea, IBD, Malabsorption
44 questions
Acute diarrhea
12 questions
Clinical evaluation and dehydration severity
3 questions
Complications
3 questions
Infectious etiologies and testing
4 questions
Treatment principles
2 questions
Chronic diarrhea and malabsorption
11 questions
Categorization approach
3 questions
Celiac disease
3 questions
Microscopic colitis and bile acid diarrhea
2 questions
Pancreatic exocrine insufficiency
3 questions
Constipation and IBS
11 questions
Constipation evaluation
3 questions
Defecatory disorders
2 questions
IBS subtypes and diagnosis
3 questions
Treatment strategies
3 questions
Inflammatory bowel disease (IBD)
10 questions
Acute severe colitis and toxic megacolon
3 questions
Diagnosis and monitoring
3 questions
Therapy overview
2 questions
UC vs Crohn differentiation
2 questions
General Internal Medicine
158 questions
Perioperative & Consultative Medicine
47 questions
Perioperative medication management
12 questions
Anticoagulants/antiplatelets
3 questions
Antihypertensives and cardiac meds
3 questions
Diabetes medications
3 questions
Steroids and immunosuppression
3 questions
Perioperative pulmonary evaluation
11 questions
Postoperative pulmonary complications
4 questions
Pulmonary testing
2 questions
Risk assessment and optimization
3 questions
Ventilation/oxygenation issues post-op
2 questions
Postoperative medical complications
11 questions
AKI and fluid/electrolyte disorders
3 questions
Delirium prevention and management
2 questions
Fever and infection workup post-op
3 questions
VTE prophylaxis
3 questions
Preoperative cardiovascular evaluation
13 questions
Arrhythmias and devices
3 questions
Functional capacity and risk stratification
3 questions
Heart failure and valvular disease periop issues
4 questions
Management of ischemic heart disease
3 questions
Prevention, Screening & Health Maintenance
47 questions
Adult immunizations
14 questions
Age- and risk-based vaccines
3 questions
Routine adult vaccines
5 questions
Vaccine contraindications and adverse events
3 questions
Vaccines in special populations
3 questions
Cancer screening (board-level principles)
12 questions
Breast and cervical screening
3 questions
Colorectal cancer screening
3 questions
Lung cancer screening
3 questions
Prostate cancer screening
3 questions
Cardiometabolic prevention
12 questions
ASCVD risk estimation and statins
3 questions
Aspirin in prevention (principles)
3 questions
Diabetes prevention and screening
3 questions
Hypertension screening and prevention
3 questions
Infectious disease prevention counseling
9 questions
Hepatitis screening
2 questions
STI screening and prevention
2 questions
TB screening (risk-based)
2 questions
Travel health basics
3 questions
Transitions of Care, Patient Safety & Cross-cutting Skills
64 questions
Medication reconciliation and deprescribing
12 questions
Adherence and access barriers
3 questions
High-risk medications
3 questions
Polypharmacy management
3 questions
Transitions and communication
3 questions
Nutrition and obesity (generalist)
14 questions
Dietary patterns in chronic disease
4 questions
Enteral and parenteral nutrition (principles)
4 questions
Malnutrition assessment
4 questions
Obesity management overview
2 questions
Occupational and environmental medicine (intro)
12 questions
Fitness for duty and return-to-work
2 questions
Reporting and public health coordination
3 questions
Toxins and exposures
3 questions
Work-related lung disease
4 questions
Palliative care fundamentals
14 questions
Ethics at end-of-life (overview)
3 questions
Goals-of-care and advance care planning
4 questions
Hospice eligibility concepts
3 questions
Symptom management
4 questions
Substance use disorders (generalist approach)
12 questions
Alcohol use disorder
3 questions
Opioid use disorder
3 questions
Stimulants and other substances
3 questions
Tobacco and vaping
3 questions
Hematology and Oncology
192 questions
Hematologic Malignancies & Solid Tumor Principles
50 questions
Leukemias (acute and chronic) overview
12 questions
Acute leukemia recognition
3 questions
Chronic leukemias basics
3 questions
Supportive care
3 questions
Treatment complications
3 questions
Lymphoma (Hodgkin and non-Hodgkin) overview
14 questions
Clinical presentation and staging basics
3 questions
Complications
4 questions
Diagnostic approach
3 questions
Treatment concepts
4 questions
Plasma cell disorders
12 questions
Amyloidosis (clinical)
3 questions
MGUS vs smoldering vs multiple myeloma
3 questions
Myeloma complications
2 questions
Treatment overview
4 questions
Solid tumors: general principles
12 questions
Cancer-associated thrombosis
3 questions
Cancer screening and early detection integration
3 questions
Oncologic pain and symptom control
3 questions
Staging and performance status (overview)
3 questions
Oncologic Emergencies & Treatment Toxicities
52 questions
Febrile neutropenia
11 questions
Empiric antibiotic choices (principles)
3 questions
Growth factors and prophylaxis concepts
3 questions
Risk stratification and initial steps
2 questions
Source control and complications
3 questions
Hypercalcemia of malignancy
11 questions
Acute management
3 questions
Diagnostic approach
2 questions
Mechanisms
3 questions
Prevention of recurrence
3 questions
Immune- and targeted-therapy toxicities (overview)
10 questions
CAR-T and bispecific toxicities (overview)
2 questions
Checkpoint inhibitor immune-related adverse events
3 questions
Chemotherapy organ toxicities (select)
3 questions
Radiation-related complications (overview)
2 questions
Spinal cord compression and brain metastasis (overview)
11 questions
Complications
2 questions
Immediate management
3 questions
Leptomeningeal disease (overview)
3 questions
Recognition
3 questions
Tumor lysis syndrome (TLS)
9 questions
Diagnosis and labs
2 questions
Prevention
3 questions
Risk assessment
2 questions
Treatment
2 questions
Red Cell Disorders & Anemia
45 questions
Approach to anemia
9 questions
Iron studies interpretation
2 questions
MCV-based framework
3 questions
Reticulocyte index and marrow response
2 questions
When to refer/urgent evaluation
2 questions
Hemolytic anemia
13 questions
Confirming hemolysis
3 questions
Immune hemolysis
3 questions
Inherited and acquired non-immune hemolysis (overview)
4 questions
Microangiopathic hemolysis (MAHA)
3 questions
Iron deficiency anemia
12 questions
Complications
3 questions
Etiologies by demographic
3 questions
Refractory/complex cases
3 questions
Treatment
3 questions
Macrocytic anemia and B12/folate disorders
11 questions
Megaloblastic anemia
4 questions
Non-megaloblastic macrocytosis
3 questions
Transfusion principles in anemia
2 questions
Treatment and safety
2 questions
White Cell Disorders, Platelets, Coagulation & Transfusion
45 questions
Coagulation disorders and bleeding
12 questions
Anticoagulant-associated bleeding
3 questions
Approach to abnormal PT/aPTT
3 questions
DIC
3 questions
Hemophilia and vWD (overview)
3 questions
Leukocytosis and leukopenia
10 questions
Eosinophilia approach
2 questions
Lymphocytosis differential
2 questions
Neutropenia approach
3 questions
Neutrophilia differential
3 questions
Thrombocytopenia and platelet disorders
12 questions
Approach to thrombocytopenia
3 questions
HIT
3 questions
ITP
3 questions
Platelet function disorders (overview)
3 questions
Transfusion medicine
11 questions
Blood components and indications
2 questions
Patient blood management
3 questions
Special transfusion scenarios
3 questions
Transfusion reactions
3 questions
Infection and Immunity
198 questions
Antimicrobial Stewardship & Resistance
39 questions
Infection prevention and control
14 questions
Antimicrobial prophylaxis (select)
4 questions
Healthcare-associated infection prevention
3 questions
Post-exposure prophylaxis (overview)
3 questions
Standard and transmission-based precautions
4 questions
Principles of empiric therapy
12 questions
Duration and follow-up
3 questions
Host and site considerations
3 questions
Local resistance patterns
3 questions
Narrowing therapy
3 questions
Resistant organisms (overview)
13 questions
C. difficile prevention and recurrence
3 questions
ESBL/AmpC and CRE
3 questions
MRSA
3 questions
Pseudomonas and nonfermenters
4 questions
Core Infectious Syndromes & Sepsis
49 questions
CNS infections (overview)
13 questions
Bacterial meningitis
3 questions
Brain abscess
3 questions
Encephalitis
4 questions
TB/fungal meningitis (overview)
3 questions
Community-acquired infections (syndrome-based)
10 questions
Bacteremia of unclear source
2 questions
Pneumonia
3 questions
Skin and soft tissue infections
2 questions
UTI and pyelonephritis
3 questions
Endocarditis and intravascular infections
14 questions
Complications
3 questions
Device and line infections
4 questions
Diagnosis
4 questions
Empiric and targeted therapy concepts
3 questions
Sepsis and septic shock
12 questions
Adjunctive care
3 questions
Early antimicrobial therapy
3 questions
Recognition and initial resuscitation
3 questions
Source control
3 questions
Immunity, Rheumatology & Vasculitis (Board-Level)
62 questions
Approach to fever and inflammation of unclear source
12 questions
Adult-onset Still disease and HLH (overview)
3 questions
FUO framework
3 questions
Inflammatory markers interpretation
3 questions
Temporal arteritis and PMR
3 questions
Immunodeficiency and allergy (overview)
13 questions
Anaphylaxis and severe allergy
2 questions
Angioedema
3 questions
Primary immunodeficiency red flags
3 questions
Secondary immunodeficiency
5 questions
Rheumatoid arthritis and spondyloarthropathies (overview)
13 questions
Crystal arthropathies vs infection
3 questions
DMARDs/biologics safety (interface)
3 questions
RA diagnosis and extra-articular disease
3 questions
Spondyloarthritis
4 questions
Systemic lupus erythematosus (SLE)
12 questions
Clinical patterns and serologies
3 questions
Major organ involvement
3 questions
Pregnancy considerations (overview)
3 questions
Treatment principles
3 questions
Vasculitis syndromes (overview)
12 questions
ANCA-associated vasculitis
2 questions
Immune complex vasculitis
4 questions
Large-vessel vasculitis
3 questions
Vasculitis mimics and infection overlap
3 questions
Special Pathogens & Host States
48 questions
Fungal infections (overview)
12 questions
Candidemia
3 questions
Cryptococcosis
3 questions
Endemic mycoses
3 questions
Invasive aspergillosis and mucormycosis
3 questions
HIV medicine (core IM level)
11 questions
Antiretroviral therapy principles
3 questions
Diagnosis and monitoring
3 questions
Opportunistic infections (recognize and prevent)
3 questions
Preventive care in HIV
2 questions
Travel and zoonoses (select)
13 questions
Arboviruses
4 questions
Malaria
3 questions
Rabies and animal bites
3 questions
Tick-borne diseases (US-focused overview)
3 questions
Tuberculosis and NTM (overview)
12 questions
Active TB
3 questions
Extrapulmonary TB (overview)
3 questions
Latent TB infection (LTBI)
3 questions
Nontuberculous mycobacteria
3 questions
Metabolic and Renal Medicine
204 questions
Diabetes & Metabolic Disorders
48 questions
Diabetic emergencies
11 questions
DKA vs HHS differentiation
2 questions
Euglycemic DKA
2 questions
Hypoglycemia
3 questions
Treatment protocols (principles)
4 questions
Dyslipidemia and ASCVD prevention
13 questions
Hypertriglyceridemia
4 questions
Primary and secondary prevention frameworks
3 questions
Secondary dyslipidemias
3 questions
Statin intolerance and adverse effects
3 questions
Obesity medicine (metabolic focus)
12 questions
Anti-obesity pharmacotherapy overview
2 questions
Assessment and complications
4 questions
Bariatric surgery overview
3 questions
Lifestyle interventions
3 questions
Type 2 diabetes mellitus
12 questions
Diagnosis and targets
3 questions
Initial therapy and escalation
4 questions
Macrovascular risk reduction
2 questions
Microvascular complications
3 questions
Fluids, Electrolytes & Acid–Base
41 questions
Acid–base disorders
10 questions
Bicarbonate therapy indications (limited)
2 questions
Metabolic acidosis
3 questions
Metabolic alkalosis
2 questions
Respiratory acidosis/alkalosis
3 questions
Hypernatremia
10 questions
Diabetes insipidus management (overview)
2 questions
Etiologies and diagnosis
3 questions
Special scenarios
3 questions
Treatment principles
2 questions
Hyponatremia
11 questions
Correction safety
3 questions
Hypovolemic hyponatremia
2 questions
SIADH
3 questions
Tonicity and initial approach
3 questions
Potassium disorders
10 questions
Acid–base linkages
3 questions
Hyperkalemia
3 questions
Hypokalemia
2 questions
Periodic paralysis (overview)
2 questions
Nephrology & Urology Core
66 questions
Acute kidney injury (AKI)
14 questions
AKI management principles
3 questions
Classification and initial evaluation
3 questions
Common intrinsic causes
4 questions
Postrenal AKI
4 questions
Chronic kidney disease (CKD)
13 questions
CKD complications
3 questions
Medication considerations
4 questions
Renal replacement planning
3 questions
Staging and progression risk
3 questions
Glomerular diseases (overview)
11 questions
Common primary GN patterns
3 questions
Nephritic syndrome and RPGN
3 questions
Nephrotic syndrome
2 questions
Systemic disease GN
3 questions
Hematuria and proteinuria evaluation
15 questions
Hereditary kidney disease (overview)
4 questions
Microscopic hematuria approach
4 questions
Proteinuria approach
3 questions
Renal tubular disorders (overview)
4 questions
Nephrolithiasis and obstruction
13 questions
Acute management
3 questions
Obstructive uropathy
3 questions
Prevention
2 questions
Stone types and evaluation
5 questions
Thyroid, Adrenal, Pituitary & Calcium/Bone
49 questions
Adrenal disorders
12 questions
Adrenal insufficiency
3 questions
Cushing syndrome (overview)
3 questions
Pheochromocytoma/paraganglioma
3 questions
Primary aldosteronism
3 questions
Calcium, parathyroid, and metabolic bone disease
12 questions
Hypercalcemia evaluation and acute management
3 questions
Hypocalcemia and tetany
3 questions
Osteoporosis
3 questions
Paget disease and osteomalacia (overview)
3 questions
Hypothyroidism and hyperthyroidism
13 questions
Amiodarone and iodine effects
3 questions
Hypothyroidism evaluation and treatment
4 questions
Thyroid nodules and cancer (overview)
3 questions
Thyrotoxicosis and Graves disease
3 questions
Pituitary disorders
12 questions
Acromegaly (overview)
2 questions
Central diabetes insipidus and SIADH (interface)
4 questions
Hyperprolactinemia
3 questions
Hypopituitarism
3 questions
Neurobehavioral Medicine
150 questions
Chronic Neurology & Cognitive Disorders
46 questions
Dementia and mild cognitive impairment
11 questions
Alzheimer disease and mixed dementia
3 questions
Evaluation
3 questions
Lewy body and frontotemporal dementia (overview)
2 questions
Vascular dementia
3 questions
Multiple sclerosis and demyelinating disease (overview)
12 questions
Acute relapse management
2 questions
Diagnosis concepts
3 questions
Disease-modifying therapy overview
3 questions
Typical presentations
4 questions
Parkinsonism and movement disorders (overview)
11 questions
Ataxia and gait disorders (overview)
3 questions
Drug-induced parkinsonism
2 questions
Essential tremor
3 questions
Parkinson disease basics
3 questions
Peripheral neuropathy and radiculopathy
12 questions
Common causes
3 questions
Diagnostic testing
3 questions
Neuropathic pain management
3 questions
Pattern-based approach
3 questions
Neurologic Emergencies and Core Syndromes
58 questions
Acute headache syndromes
11 questions
Meningitis/encephalitis vs migraine differentiation
3 questions
Primary headaches (overview)
3 questions
Subarachnoid hemorrhage and thunderclap headache
2 questions
Temporal arteritis
3 questions
Altered mental status and encephalopathy
11 questions
Delirium recognition and initial workup
3 questions
Hepatic and uremic encephalopathy
3 questions
Nonconvulsive status epilepticus (overview)
3 questions
Wernicke encephalopathy
2 questions
Neuromuscular weakness and spinal cord syndromes
12 questions
Acute myelopathy and cord compression
3 questions
Critical illness neuromyopathy (overview)
3 questions
Guillain–Barré syndrome
4 questions
Myasthenia gravis and crisis
2 questions
Seizures and status epilepticus
12 questions
Antiepileptic drug adverse effects (overview)
3 questions
Common seizure mimics
3 questions
First seizure evaluation
3 questions
Status epilepticus management
3 questions
Stroke and TIA
12 questions
Acute ischemic stroke treatment principles
3 questions
Hemorrhagic stroke basics
3 questions
Initial assessment and imaging
3 questions
Secondary prevention
3 questions
Psychiatry, Substance-Related Presentations & Sleep
46 questions
Depression and anxiety in medical illness
12 questions
Depression in chronic disease (overview)
3 questions
Diagnosis and screening
3 questions
Medication interactions and side effects
3 questions
Treatment options
3 questions
Psychosis, agitation, and behavioral emergencies
13 questions
Agitation management (medical setting)
3 questions
Catatonia (overview)
3 questions
Differential diagnosis of acute psychosis
3 questions
Neuroleptic malignant syndrome and serotonin syndrome
4 questions
Sleep disorders (overview)
11 questions
Insomnia
3 questions
Obstructive sleep apnea
3 questions
Parasomnias and circadian disorders (overview)
3 questions
Restless legs syndrome
2 questions
Substance-related syndromes
10 questions
Alcohol withdrawal and complications
3 questions
Opioid intoxication and withdrawal
2 questions
Sedative-hypnotic withdrawal
2 questions
Stimulant toxicity
3 questions
Advanced
Advanced Internal Medicine
Acute and Critical Care
50 questions
Emergency Stabilization & Resuscitation
50 questions
Airway management basics for internists
15 questions
Indications and risk assessment
4 questions
Post-intubation ventilator setup (principles)
3 questions
Pre-oxygenation and RSI principles
4 questions
Special airways
4 questions
Approach to the crashing patient
12 questions
Early critical investigations
3 questions
Early escalation and teamwork
3 questions
Primary survey (ABCDE)
3 questions
Rapid differential by physiology
3 questions
ICU Complications & Organ Support
10 questions
Acute kidney injury in ICU
2 questions
ARDS and severe hypoxemia
3 questions
Delirium, immobility, and ICU-acquired weakness
2 questions
Nosocomial infections and prevention
3 questions
Shock: advanced management
13 questions
Cardiogenic shock
3 questions
Distributive shock nuances
3 questions
Hemorrhagic shock and massive transfusion
3 questions
Obstructive shock
4 questions
Advanced Clinical Medicine
650 questions
Acute and Critical Care
95 questions
Acute coronary syndromes and malignant arrhythmias (critical care)
13 questions
Bradycardia and AV block emergencies
3 questions
Post-cardiac arrest care
4 questions
STEMI/NSTEMI time-critical pathways
3 questions
Tachyarrhythmias instability management
3 questions
Acute GI bleeding and massive hemorrhage
11 questions
Bleeding in liver disease/uremia
3 questions
Lower GI bleed and ischemic colitis
3 questions
Resuscitation and hemostatic strategy
3 questions
Variceal bleeding protocol
2 questions
Acute kidney injury and renal replacement in ICU (overview)
10 questions
Complications of RRT
3 questions
CRRT vs intermittent HD concepts
2 questions
Drug dosing on RRT
3 questions
Indications and timing debates
2 questions
Acute respiratory failure and ventilation basics
12 questions
ARDS management fundamentals
4 questions
Intubation decision-making
3 questions
Noninvasive support
2 questions
Weaning and extubation
3 questions
ICU sedation, analgesia, delirium, and nutrition
12 questions
Analgesia-first sedation and monitoring
3 questions
Delirium prevention and management bundle
3 questions
ICU nutrition concepts
3 questions
Stress ulcer and DVT prophylaxis
3 questions
Sepsis bundles and ICU escalation
12 questions
Adjuncts and controversies
3 questions
Organ support
3 questions
Sepsis in special hosts
3 questions
Time-critical actions
3 questions
Severe electrolyte and acid–base emergencies
13 questions
Severe acidosis and toxic ingestions
5 questions
Severe hypercalcemia and hypocalcemia
3 questions
Severe hyperkalemia
3 questions
Severe hyponatremia with symptoms
2 questions
Shock (all types)
12 questions
Fluid resuscitation strategies
3 questions
Initial recognition and classification
3 questions
Monitoring and endpoints
3 questions
Vasopressors and inotropes
3 questions
Advanced Therapeutics
59 questions
Advanced endocrine therapeutics
12 questions
Complex insulin management
3 questions
Diabetes drugs in comorbidities
3 questions
Osteoporosis pharmacotherapy sequencing (overview)
3 questions
Thyroid disease in special contexts
3 questions
Biologics, immunosuppression, and infection prophylaxis
12 questions
Managing immune-related adverse events
3 questions
Monitoring and toxicity mitigation
3 questions
Pre-therapy screening
3 questions
Transplant-specific therapeutics overview
3 questions
Complex anticoagulation and antithrombotic management
12 questions
Antiplatelet therapy in complex CAD
3 questions
Bleeding management and reversal
4 questions
DOAC selection in complex patients
2 questions
Mechanical valves and high-risk thrombosis
3 questions
Complex antimicrobial therapy and stewardship (advanced)
12 questions
Endocarditis and osteomyelitis stewardship
4 questions
OPAT and IV-to-PO transitions
3 questions
Resistant Gram-negative infections
3 questions
Serious MRSA infections
2 questions
Oncologic supportive care and toxicity management (advanced)
11 questions
Antiemetic regimens (overview)
3 questions
Cancer pain and palliative therapeutics
3 questions
Hematopoietic growth factors and transfusions
2 questions
Immunotherapy and cellular therapy toxicities (overview)
3 questions
Complex Diagnostics
55 questions
Advanced ECG and rhythm analysis
12 questions
Brugada, long QT, and inherited arrhythmia syndromes (overview)
3 questions
Electrolyte/drug-induced ECG nuances
3 questions
Pacemaker/ICD ECG basics
3 questions
Wide complex tachycardia differentiation
3 questions
Advanced echocardiography concepts (board-relevant)
10 questions
Diastolic dysfunction and HFpEF
3 questions
Endocarditis imaging
2 questions
Shock POCUS integration
2 questions
Valvular quantification
3 questions
Advanced hematologic and immunologic diagnostics
11 questions
Autoantibodies and complement patterns
2 questions
Hemolysis and smear interpretation
3 questions
Interpreting abnormal coagulation tests
3 questions
Monoclonal gammopathy evaluation
3 questions
Advanced imaging interpretation and incidentalomas
11 questions
Incidental adrenal nodule workup (overview)
2 questions
Pulmonary nodules (overview)
2 questions
Renal masses and cysts (overview)
3 questions
Thyroid nodules (overview)
4 questions
Advanced pulmonary diagnostics
11 questions
Bronchoscopy and BAL interpretation (overview)
3 questions
Complex PFT interpretation
3 questions
Sleep study interpretation basics (overview)
3 questions
V/Q, CTPA, and CTEPH workup
2 questions
Complex Multisystem Presentations
57 questions
Complex liver–kidney–heart interactions
12 questions
Cardiorenal syndromes
3 questions
Congestive hepatopathy
2 questions
Hepatorenal and cirrhotic cardiomyopathy
4 questions
Pulmonary-renal syndromes
3 questions
Fever of unknown origin and hyperinflammatory syndromes
11 questions
Advanced diagnostics
3 questions
Advanced differential and prioritization
2 questions
Empiric therapy risks
3 questions
High-yield rare entities
3 questions
Syncope and unexplained falls (advanced)
12 questions
Autonomic and orthostatic syndromes
3 questions
Cardiac causes
3 questions
Neurologic mimics
3 questions
Risk stratification and disposition
3 questions
Undifferentiated dyspnea with multimorbidity
11 questions
Cardiac vs pulmonary vs anemia vs metabolic causes
2 questions
Complex diagnostic strategy
3 questions
Disposition decisions
3 questions
Management tradeoffs
3 questions
Unexplained weight loss and constitutional symptoms
11 questions
Cancer-focused evaluation
2 questions
Endocrine and metabolic causes
3 questions
Infectious causes
3 questions
Psychiatric and social causes
3 questions
Multimorbidity and Frailty
52 questions
Frailty assessment and prognostication
9 questions
De-intensification of care
2 questions
Frailty identification tools
3 questions
Prognostic communication
2 questions
Sarcopenia and malnutrition
2 questions
Geriatric syndromes
12 questions
Delirium
3 questions
Falls and syncope in older adults
3 questions
Incontinence
3 questions
Pressure injuries and skin care
3 questions
Polypharmacy and complex medication management
9 questions
Adherence and regimen simplification
2 questions
Deprescribing high-risk meds
2 questions
Medication prioritization with multimorbidity
2 questions
Renal/hepatic dosing in older adults
3 questions
Special Populations
11 questions
Adults with disabilities and complex care needs
3 questions
Cultural and language equity in complex care
2 questions
Homelessness and housing insecurity
3 questions
Post-ICU syndrome (overview)
3 questions
Transitions of care and post-acute planning
11 questions
Hospital readmissions and high-risk patients
2 questions
Palliative and hospice transitions
3 questions
Safe discharge planning
3 questions
Skilled nursing, rehab, home health selection
3 questions
Procedural and Perioperative Care
78 questions
Arthrocentesis and injection (overview)
11 questions
Complications and contraindications
3 questions
Indications
3 questions
Synovial fluid analysis
3 questions
When to consult orthopedics/rheumatology
2 questions
Lumbar puncture
11 questions
Complications
3 questions
CSF collection and handling
3 questions
CSF interpretation (advanced patterns)
3 questions
Indications and contraindications
2 questions
Paracentesis
11 questions
Ascitic fluid interpretation
3 questions
Complications and management
3 questions
Indications and contraindications
3 questions
Technique and ultrasound guidance
2 questions
Perioperative medicine (advanced integration)
12 questions
Cardiac risk in complex patients
3 questions
Periop anticoagulation for high thrombotic risk
3 questions
Periop management of chronic meds
3 questions
Postop complications prevention
3 questions
Procedure fundamentals
11 questions
Aseptic technique and infection prevention
2 questions
Informed consent and capacity
3 questions
Periprocedural anticoagulation management
3 questions
Sedation and analgesia principles (overview)
3 questions
Thoracentesis
12 questions
Complications
3 questions
Indications and pre-procedure evaluation
3 questions
Next steps after thoracentesis
3 questions
Pleural fluid studies
3 questions
Vascular access (peripheral and central) overview
10 questions
Indications for central venous access
2 questions
Line complications
3 questions
Midlines and PICCs (selection concepts)
3 questions
Ultrasound guidance principles
2 questions
Professionalism and Ethics
52 questions
Capacity, consent, and surrogate decision-making
10 questions
Advance directives and POLST/MOLST concepts
2 questions
Capacity assessment
2 questions
Informed consent in complex care
3 questions
Surrogates and substituted judgment
3 questions
Confidentiality, privacy, and mandatory reporting (principles)
12 questions
Adolescent confidentiality (overview)
2 questions
Confidentiality in routine care
4 questions
Exceptions to confidentiality (overview)
3 questions
Subpoenas, documentation, and medicolegal basics
3 questions
End-of-life ethics and high-stakes decisions
9 questions
DNR/DNI and code status discussions
2 questions
Organ donation and donation after circulatory death (overview)
2 questions
Palliative sedation (overview)
3 questions
Withholding vs withdrawing life-sustaining treatment
2 questions
Error disclosure and communication in adverse events
9 questions
Documentation after adverse events
2 questions
Duty of candor principles
2 questions
Root cause analysis participation
3 questions
Second victim phenomenon
2 questions
Professional conduct, conflict of interest, and boundaries
12 questions
Conflict of interest in prescribing and research
3 questions
Cultural humility and respectful care
3 questions
Fitness to practice and impairment
3 questions
Professional boundaries
3 questions
Rare and Niche-but-Testable Diseases
44 questions
Amyloidosis (systemic)
11 questions
Clinical phenotypes
3 questions
Diagnostic strategy
3 questions
Red flags
2 questions
Types and treatment overview
3 questions
Endocrine emergencies (advanced)
11 questions
Adrenal crisis
2 questions
Hypercalcemic crisis
2 questions
Pituitary apoplexy
3 questions
Thyroid storm and myxedema coma
4 questions
Porphyria and other metabolic masqueraders (overview)
11 questions
A1AT deficiency
3 questions
Acute intermittent porphyria
3 questions
Hereditary hemochromatosis
3 questions
Wilson disease
2 questions
Sarcoidosis
11 questions
Diagnosis and mimics
3 questions
Hypercalcemia mechanism
2 questions
Organ involvement patterns
4 questions
Treatment principles
2 questions
Scholarship and Education
46 questions
Critical appraisal and statistics (advanced applied)
12 questions
Clinical prediction models and AI (overview)
3 questions
Diagnostic studies
3 questions
Interpreting RCTs and pragmatic trials
3 questions
Systematic reviews and guidelines
3 questions
Reflective practice and lifelong learning
10 questions
Clinical reasoning reflection and calibration
2 questions
Continuing professional development (CPD) planning
2 questions
Professional development and leadership learning
4 questions
Well-being and burnout prevention
2 questions
Scholarly activity and research literacy
12 questions
Ethics and IRB basics
4 questions
Formulating clinical questions
3 questions
Presentation and dissemination skills
2 questions
Quality improvement scholarship
3 questions
Teaching, supervision, and bedside education
12 questions
Clinical teaching frameworks
3 questions
Feedback and assessment
3 questions
Remediation and coaching (overview)
4 questions
Supervision and entrustment
2 questions
Special Populations
57 questions
Adolescent transition to adult care
9 questions
Adolescent mental health and substance risk
3 questions
Congenital heart disease in adults (overview)
1 question
Cystic fibrosis and chronic childhood diseases (overview)
3 questions
Transition planning
2 questions
Health equity in special populations
12 questions
Bias mitigation in clinical decisions
3 questions
Language, disability, and communication access
3 questions
Population health approaches (overview)
3 questions
Structural determinants and outcomes
3 questions
Immunocompromised host (non-transplant and transplant interfaces)
12 questions
Drug interactions
3 questions
Fever in immunocompromised patient
3 questions
Prophylaxis concepts
3 questions
Vaccination strategies
3 questions
Occupational, travel, and environmental illness (advanced)
13 questions
Altitude and diving medicine (overview)
3 questions
Heat illness and exertional syndromes
3 questions
Toxic exposures
4 questions
Travel fever evaluation
3 questions
Pregnancy interfaces for internists
11 questions
Diabetes in pregnancy (overview)
3 questions
Hypertensive disorders of pregnancy (overview)
3 questions
Medication safety counseling
3 questions
Thromboembolism in pregnancy (overview)
2 questions
Systems Leadership and Quality
55 questions
Clinical governance and stewardship
12 questions
Antimicrobial stewardship
3 questions
Clinical pathways and standard work
3 questions
Diagnostic stewardship
3 questions
Resource utilization and cost awareness
3 questions
Handoffs, escalation, and team leadership
11 questions
Interprofessional teamwork and conflict management
3 questions
Leadership in crisis
2 questions
Rapid response and deterioration management
3 questions
Safe handoff practices
3 questions
Patient safety fundamentals
11 questions
High reliability principles
3 questions
Human factors and ergonomics
3 questions
Safety event reporting and learning systems
2 questions
Types of harm and error
3 questions
Population health and service management (overview)
10 questions
Care for high-utilizer populations
2 questions
Clinical operations basics
3 questions
Ethical resource allocation
3 questions
Public health collaboration
2 questions
Quality improvement methodology
11 questions
Equity in QI
3 questions
Implementation science basics
2 questions
Measuring quality
3 questions
QI tools and frameworks
3 questions
Advanced Therapeutics
209 questions
High-Risk Medication Management & Monitoring
46 questions
Biologic therapies (deep safety)
12 questions
Infusion reactions and hypersensitivity
3 questions
Long-term monitoring
3 questions
Managing serious infections on biologics
3 questions
Pre-treatment evaluation and vaccination
3 questions
Complex heart failure therapeutics
11 questions
Advanced devices and palliative transitions
3 questions
Atrial fibrillation in HF
2 questions
Diuretic resistance
3 questions
GDMT optimization under constraints
3 questions
Multimorbidity and competing guideline targets
12 questions
Benefit–harm assessment
3 questions
Deprescribing and simplification at scale
3 questions
High-risk transitions (hospital to home)
3 questions
Therapeutic monitoring plans
3 questions
Therapeutics in advanced CKD and dialysis
11 questions
Antibiotic dosing on RRT
3 questions
Anticoagulation in CKD/ESRD
2 questions
Diabetes management in CKD
3 questions
Pain and sedation in CKD
3 questions
Multimorbidity and Frailty
34 questions
Complex chronic disease clustering
11 questions
Cancer survivorship with multimorbidity
3 questions
Cirrhosis + renal dysfunction + malnutrition
3 questions
COPD + HF + sleep apnea overlap
3 questions
Diabetes + CKD + HF interplay
2 questions
Frailty-focused acute care decisions
10 questions
Avoiding iatrogenesis
2 questions
Delirium prevention in high-risk patients
3 questions
Falls prevention programs
2 questions
ICU admission and escalation decisions
3 questions
Special Populations
13 questions
Caregiver burden and social support
2 questions
Dementia and medical decision-making
3 questions
Geriatric oncology (overview)
4 questions
Palliative integration for chronic organ failure
4 questions
Procedural and Perioperative Care
23 questions
Advanced perioperative risk management
11 questions
High-risk cardiac conditions
4 questions
Periop anticoagulation in high thrombotic risk
3 questions
Periop diabetes and obesity considerations
2 questions
Pulmonary hypertension and right heart failure periop
2 questions
Complication-aware procedural practice
12 questions
Arterial blood gas and arterial line basics (overview)
3 questions
Lumbar puncture and anticoagulation management
3 questions
Thoracentesis/paracentesis complications management
3 questions
Ultrasound-guided procedures (POCUS integration)
3 questions
Professionalism and Ethics
21 questions
Complex goals-of-care conversations
11 questions
Managing conflict with families
2 questions
Moral distress and clinician support
3 questions
Serious illness communication
3 questions
Time-limited trials and ICU decisions
3 questions
Consent and capacity in high-risk settings
10 questions
Advance directives interpretation under uncertainty
2 questions
Cultural and language barriers
3 questions
Emergency exceptions to consent
2 questions
Refusal of care
3 questions
Scholarship and Education
20 questions
Clinical scholarship and guideline implementation
10 questions
Academic integrity and authorship
3 questions
Guideline interpretation and local adaptation
2 questions
Journal club leadership
2 questions
Teaching diagnostic reasoning
3 questions
Designing curricula and assessments
10 questions
Assessment methods
3 questions
Feedback systems at program level
3 questions
Learning objectives and alignment
2 questions
Standard setting concepts (overview)
2 questions
Special Populations
43 questions
Complex care in pregnancy (IM interface)
12 questions
Autoimmune disease in pregnancy
3 questions
Cardiac disease and pregnancy (overview)
3 questions
Thyroid disease and pregnancy
3 questions
VTE and thrombophilia
3 questions
Health equity and culturally safe care
10 questions
Care for migrants and refugees (overview)
3 questions
Reducing disparities in chronic disease outcomes
2 questions
Trauma-informed care and stigma reduction
2 questions
Working with interpreters and low health literacy
3 questions
Immunocompromised hosts (advanced)
10 questions
Biologic therapies and latent infections
3 questions
HIV with complex comorbidities
2 questions
Post-transplant infectious syndromes (overview)
2 questions
Vaccination strategy in immunocompromise
3 questions
Occupational and travel medicine (advanced)
11 questions
Mass gathering medicine (overview)
4 questions
Return-to-work and disability
2 questions
Tropical medicine red flags
3 questions
Work-related lung and skin disease
2 questions
Systems Leadership and Quality
22 questions
Leading QI projects in clinical services
11 questions
Change management
3 questions
Choosing an aim and measures
3 questions
Data interpretation
2 questions
Spreading improvements
3 questions
Service management and patient flow
11 questions
Capacity and throughput
3 questions
Handoffs across services
3 questions
Resource stewardship
3 questions
Safety culture and speaking up
2 questions
Complex Diagnostics
35 questions
Bayesian & Stewardship-Based Diagnostics (Advanced)
35 questions
Advanced Bayesian reasoning in practice
11 questions
Calibration and diagnostic confidence
3 questions
Decision thresholds and shared decisions
2 questions
Diagnostic timeouts and debiasing
4 questions
Sequential testing strategy
2 questions
Advanced imaging and pattern recognition
12 questions
Abdominal imaging pearls
3 questions
Complex chest CT patterns
4 questions
Incidentalomas and overdiagnosis management
3 questions
Neuroimaging red flags
2 questions
Complex lab interpretation and pitfalls
12 questions
Autoimmune serologies pitfalls
3 questions
Endocrine test pitfalls
3 questions
Microbiology test interpretation
3 questions
Spurious results and artifacts
3 questions
Multimorbidity and Frailty
30 questions
Geriatric Medicine at Advanced Level
30 questions
Advanced polypharmacy in frailty
11 questions
Adverse drug event prevention
2 questions
Deprescribing complex regimens
3 questions
Medication management systems
3 questions
Renal dosing and monitoring in older adults
3 questions
Comprehensive geriatric assessment (CGA)
10 questions
Documentation and communication
2 questions
Domains of CGA
3 questions
Frailty and surgical/ICU risk
3 questions
Using CGA to guide care plans
2 questions
Symptom control in multimorbidity
9 questions
Anorexia-cachexia and nutrition
3 questions
Dyspnea management across diseases
2 questions
Insomnia and behavioral symptoms
2 questions
Pain management in frail older adults
2 questions
Procedural and Perioperative Care
23 questions
Advanced Procedural Competence and Perioperative Optimization
23 questions
Perioperative care for high-risk medications
12 questions
Anticoagulants and antiplatelets (advanced)
3 questions
Diabetes therapies periop
3 questions
Immunosuppressants periop
3 questions
Pain and sedation risk reduction
3 questions
Ultrasound-guided bedside procedures (advanced)
11 questions
Ascites procedures
3 questions
Pleural procedures
2 questions
POCUS for diagnosis and guidance
3 questions
Vascular access
3 questions
Professionalism and Ethics
23 questions
Advanced Ethics in Complex Internal Medicine
23 questions
Ethics consultation triggers and frameworks
11 questions
Documentation and communication
4 questions
Ethics in resource limitation
2 questions
Identifying ethical dilemmas
2 questions
Structured analysis
3 questions
Professionalism in difficult interactions
12 questions
Conflicts of interest in leadership roles
3 questions
Equity and bias in professionalism
3 questions
Interprofessional conflict resolution
3 questions
Managing disruptive behavior
3 questions
Scholarship and Education
22 questions
Advanced Educator and Scholar Competencies
22 questions
Learning science and curriculum design (overview)
11 questions
Cognitive load and instructional design
2 questions
Competency-based medical education (CBME)
3 questions
Faculty development and coaching
3 questions
Simulation-based education
3 questions
Scholarly writing and dissemination
11 questions
Academic career development
3 questions
Educational scholarship
3 questions
Presentation skills
3 questions
Writing for publication
2 questions
Special Populations
34 questions
High-Risk and Under-Served Groups (Advanced)
34 questions
Care of patients with advanced cancer and comorbidities
13 questions
Complications of therapy affecting other organs
4 questions
Decision-making under limited prognosis
2 questions
Infection risk management
4 questions
Transitions to hospice
3 questions
Patients with serious mental illness
10 questions
Capacity and adherence challenges
3 questions
Delirium vs psychiatric symptom overlap
2 questions
Metabolic monitoring for antipsychotics
2 questions
Suicide risk in medical illness
3 questions
Patients with substance use disorders and complex illness
11 questions
Hospital-based addiction care
3 questions
Infections related to injection drug use
3 questions
Pain management with OUD
3 questions
Trauma-informed care
2 questions
Structured oral examination (SOE)
797 questions
Unspecified domain
797 questions
Acute cognitive change assessment in Internal Medicine
8 questions
Acute coronary syndrome (ACS) with comorbidity modification
8 questions
Acute decompensated heart failure and cardiorenal syndrome
8 questions
Acute hypercapnic respiratory failure
6 questions
Acute kidney injury (AKI) evaluation and prevention
8 questions
Acute liver failure management and escalation
8 questions
Acute monoarthritis evaluation and safe therapy selection
7 questions
Acute pancreatitis diagnosis, severity stratification, and complications
8 questions
Advanced therapeutics and systems leadership
8 questions
Anemia evaluation and cancer screening
8 questions
Anticoagulation complications and reversal
8 questions
Applying evidence to patient-centered decisions
8 questions
Arrhythmia risk evaluation and prevention
8 questions
Atrial fibrillation in acute illness
8 questions
Biliary sepsis and urgent source control
7 questions
Cardiogenic shock stabilization and escalation
8 questions
Cavitary lung disease differential diagnosis
9 questions
Chronic diarrhea diagnostic reasoning and IBD management
8 questions
Cirrhosis complications and bedside procedure safety
8 questions
CNS infection initial management and procedural decision-making
8 questions
Complex diagnostics and rapid physiologic assessment
8 questions
Complex symptom-based diagnostic reasoning
8 questions
Complex symptom management and safe prescribing
8 questions
Comprehensive geriatric assessment and individualized goal setting
8 questions
Comprehensive preventive care in Internal Medicine
8 questions
Delirium prevention and management in critical care
8 questions
Determination of death and donation processes
8 questions
Diabetes complications and limb salvage
8 questions
Diabetic ketoacidosis (DKA) management
8 questions
Diagnostic reasoning and diagnostic safety
8 questions
Diagnostic reasoning education and test stewardship
8 questions
Dysphagia evaluation and cancer pathways
8 questions
Edema differential diagnosis using physiology
8 questions
End-of-life decision-making in Internal Medicine
8 questions
Endocrine emergency management with cardiopulmonary complications
7 questions
Environmental emergency with multi-organ complications
8 questions
Ethics, capacity, and emergency treatment boundaries
7 questions
Febrile neutropenia and catheter-related infection
8 questions
Fever evaluation under immunosuppression
8 questions
Fulminant sepsis with public health interface
7 questions
FUO workup with endocarditis consideration
8 questions
GI bleeding resuscitation and portal hypertension complications
8 questions
Hematologic emergency recognition and plasma exchange pathway
8 questions
Hemorrhagic shock, anticoagulation reversal, and endoscopy coordination
8 questions
HHS and concurrent cardiovascular events
8 questions
High-severity pneumonia and escalation decisions
8 questions
High-stakes neurologic diagnostic strategy
8 questions
Hospital-acquired infection management
8 questions
HSV encephalitis recognition and treatment
8 questions
Hypercalcemia diagnosis and emergency treatment
8 questions
Hypertensive emergency recognition and organ protection
8 questions
Hyponatremia workup and safe correction
8 questions
Infective endocarditis diagnosis and complications
8 questions
Integrative diagnostic reasoning across systems
8 questions
Kidney stones with systemic risk factor management
8 questions
Life-threatening electrolyte disturbance management
8 questions
Macrocytic anemia and neurologic integration
8 questions
Medication-related harm in multimorbidity
9 questions
Medication adverse effect recognition and alternative anticoagulation
8 questions
Modern therapeutics adverse event recognition
8 questions
Movement disorder evaluation with autonomic complications
8 questions
Nephritic syndrome and rapidly progressive GN approach
8 questions
Nephrotic syndrome complications and hypercoagulability
8 questions
Neurobehavioral medicine in medical settings
8 questions
Neurocritical stabilization and cause finding
8 questions
Obstetric medicine interface for internists
8 questions
Oncologic emergency recognition
8 questions
Oncologic metabolic emergency and renal protection
9 questions
Opportunistic infection recognition and management
8 questions
Patient safety event management and professionalism
8 questions
Pericarditis diagnosis and treatment
8 questions
Perioperative risk stratification and optimization
8 questions
Pleural effusion evaluation and procedural safety
8 questions
Procedural planning and medication safety
8 questions
Quality improvement and infection prevention
8 questions
Rare-but-serious diagnostic consideration
8 questions
Respiratory failure and ventilator management
8 questions
Resuscitation and high-risk PE management
8 questions
Risk trade-offs in complex chronic disease
8 questions
Safe transitions of care in Internal Medicine
8 questions
Sepsis recognition with frailty and delirium risk
8 questions
Severe hypothyroidism emergency care
8 questions
Shock differential and endocrine rescue therapy
8 questions
Shock management and organ support in critical care
8 questions
Status asthmaticus stabilization and escalation
8 questions
Stroke reperfusion decision-making
8 questions
Syncope evaluation and valvular heart disease
8 questions
Systemic autoimmune disease with pulmonary involvement
8 questions
Systemic lupus flare with multi-organ involvement
8 questions
Systems-based practice and ethical allocation
8 questions
TIA evaluation and vascular risk management
8 questions
Time-critical chest pain differential and emergency management
8 questions
Time-critical neurologic presentation triage
9 questions
Toxicology, airway, and safe antidote use
8 questions
Toxicology and withdrawal management
8 questions
Transfusion medicine emergency and systems response
8 questions
Undifferentiated dyspnea and integrated cardiopulmonary management
8 questions
Vasculitis emergency recognition and management
8 questions
VTE diagnosis and anticoagulation initiation
8 questions
Whole-patient internal medicine: prioritization, deprescribing, and safe discharge
8 questions
Systems Leadership and Quality
20 questions
Advanced Systems Practice and Leadership
20 questions
Designing and evaluating care pathways
10 questions
Clinical pathway creation
3 questions
High-value care integration
2 questions
Measuring impact
3 questions
Sustainability and spread
2 questions
Leading high-reliability teams
10 questions
Crisis management and incident command (overview)
3 questions
Safety culture measurement and improvement
3 questions
Standardization vs flexibility
2 questions
Team cognition and situational awareness
2 questions
Prepare for your examination
ABIM Internal Medicine Certification Examination
The American Board of Internal Medicine (ABIM) Internal Medicine Certification Examination is an initial-certification exam of up to 240 single-best-answer questions across four sessions. Its January 2026 blueprint assigns the largest share to Cardiovascular Disease; passing the exam is one part of a broader certification pathway.
Verified 18 Oct 2026
Read exam guideMembership of the Royal College of Physicians of Ireland in General Medicine
The Royal College of Physicians of Ireland’s MRCPI in General Medicine is a three-component examination sequence: Part I Written, Part II Written, and Part II Clinical. This guide explains their formats, published blueprints, progression rules, and preparation priorities. Passing the examination sequence is not the same as completing Higher Specialist Training.
Verified 18 Oct 2026
Read exam guideMembership of the Royal Colleges of Physicians of the United Kingdom
Understand how the three MRCP(UK) examinations assess medical knowledge, applied clinical decisions, and observed clinical skills, and plan preparation around their formats and progression rules.
Verified 18 Oct 2026
Read exam guideRACP Adult Internal Medicine Divisional Examinations
The RACP Adult Internal Medicine Basic Training examination family comprises the Divisional Written Examination (DWE) and Divisional Clinical Examination (DCE). This guide covers the October 2026 DWE format and blueprint, the DCE’s real-patient cases, and eligibility—including first-time candidate changes applying from 2027.
Verified 18 Oct 2026
Read exam guide